Synpromics: Scotland’s Latest Biotech Company

Synpromics announces it incorporation as Scotland’s latest biotech company. The new company aims to focus its activities in the area of synthetic mammalian biology and has acquired a number of patent applications that arose out of inventions by its founder and managing director; Dr Michael Leslie Roberts.

Synpromics’ technology will centre on the development of synthetic promoters for application as research, diagnostic and therapeutic tools. Synthetic promoters are relative short segments of man-made DNA that can specifically control the activity of any gene of interest. Synpromics has developed a method whereby the activity of the gene can be controlled depending on its environment.

“This is a very exciting time for Synpromics” states its founder Dr. Roberts. “It is the realisation of several years work and we believe we have the potential to change how researchers use gene expression tools. Our technology has more subtle applications in the Diagnostics Industry and we are currently developing a number of such tools. We would also like to partner with companies developing gene therapies so that we can ultimately see our technology used in the development of safer and more effective genetic medicines.”

This technology centres on the exploitation of a cell’s unique gene expression profile, which changes depending on the environmental setting in which the cell resides. Therefore, if a cell is in a diseased state, or if it is infected with a pathogen or treated with a chemical or biological agent then its gene expression profile will change. Likewise, cells derived from different tissues each contain a unique gene expression profile specific to the tissue of origin. Therefore, given that each unique gene expression profile is the result of the balance of the activities of a range of transcription factors and their corresponding cis-regulatory elements, it is possible to design synthetic promoters that can be active only under that specific profile.

Synpromics has acquired the means to create these synthetic promoters and thus control gene expression in a variety of pathological conditions; active in response to infection or treatment; or specific to any tissue in any organism. This has obvious applications in a variety of areas, such as life sciences R&D, diagnostics and in the development of novel gene therapies with higher specific activity.

Synpromics is currently seeking to enter into discussions with interested distributors so that it can establish a network of collaborators with a view to commercially exploit its technology. For more information contact Dr Roberts at the following email address: